en Cuevana 3. One in five Americans are diagnosed with mental illness every year. Suicide is the second most common cause of death in the US for youth aged 15-24, and kills over 800,000 people globally per year. Drug overdose kills 81,000 in the US annually. The autoimmune disorder epidemic affects 24 million people in the US alone. What is going on? The interconnected epidemics of anxiety, chronic illness and substance abuse are, according to Dr. Gabor Maté, normal - but not in the way you might think.